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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d83ba04ae57cad422e3eba4c8e44b2c5f1f971ee00ede045d62c6551f19f749' 
  AND token = 'GhVjoeivauOUhRyYCpfmA2jBaLCL1djuGxiT3atJT3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}