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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c2af773b9edb94d50816d09ee93c4f68981d64936fdc012b90bb5a382cf8cc' 
  AND token = '23txsVJBP6i/30WFrXLm8+kIoCmImKyWNRLWxJKOwcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}