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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '652f5003b080b60fe30b6a659421e5b9e9ea190576bc9b91fa835f5322399135' 
  AND token = '9H+g5vm01X64lEtJF51NwnikxdcbdCr2EIqMNusMgOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}