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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad0a27927e2ca948999ee4ec1625c920f2dd4feb760d5731cef775f008d72c0' 
  AND token = 'GnaajxvCpbKMA9TqmcgI0MagGJhx32FWFGExGdTa2CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}