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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1e862cd3dd5909ddc14b913ab8deb0531a7f4f440c017df587023c9d78e593' 
  AND token = 'OPbcQwg5414rnB34JvDCsxFtMZd9eTczqlQb9kbQMtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}