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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01dfa78812fd5766e929a5d629e0fbd3df9cc2190223063c152df4aca1d85b21' 
  AND token = 'yyLrnIWynE6ZjosFkISj3N2sNG7TeLeSpmVE1tzuIaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}