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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '521d557480ac6cbfacfc759402cf4559aa1f8609314636a5261de6b0c5e72f72' 
  AND token = 'cd3/hg3M+UT9LjTALYr/Wip8eoBHzdreR2/H2ktwgVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}