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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645f5b7fc261cbf9c40bbabe6f4b9c7a1a249a27247d3be8429849b9c28f8cc1' 
  AND token = 'deIiNTN2zLWUqgLpAXLWqTx8ayM81jbEs10dGmz5Hos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}