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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e13d634a8770f88645cd129144b5f75dc8ceb0a1102b0ebd52380193bb3b4a' 
  AND token = 'AIYEGZA1ZNZdFrt6r1M2TUFi7JbRAh+hv5n8EOP2c74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}