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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb800815d47b374533fc4892c178f6b27675e222bb0133fdd5d2acbc012e6052' 
  AND token = 'dvV5U9V7zwseB1C6EFfLvTBPiz14nhVtzFxUnoN5DAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}