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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3be257ede1b21d495e2807cd4cb54e3c6f77a1044964926cd071f01aa711644' 
  AND token = 'SZ2cTZ8VpFJkXlDzIuj+jFiyXlKDVCB2pUEg2jSuFfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}