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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0240798479079e8d2c7120ee7deb0b458516b22b595b76fa59f266da2ee08745' 
  AND token = 'MQulD3WCdiFsgIt8p/CjB4PW4EeelDaFDso+1hAdsIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}