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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b9afafd8dca93ab5d8c626a6fc77ddac10d7b59737f2734251267f5942f3f33' 
  AND token = 'Tj80f3Vmg9Ceehy5bGFKDcHxYB9LP9ma8qC8x/5CAko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}