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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4acf1f9637efe795d853d0b6900d837324222f5260fa89f6d477b075e4f6b7' 
  AND token = 'CvHpxLVMUDlYf79x2TtA0voZPCmtNstHmm/Cjzv3oV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}