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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ddbbbe2e394c93d278ebee8431d8ea5fe12b82e454d54d3f6dacc8b85624638' 
  AND token = 'effP/ZY2pv1748UU8Nvn16bwq/QlpoLvsIrBcE+NUMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}