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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740f914d4c66d6e6bdb505ac7f34959436976b0b1a56fadc169b585ee5c3bc46' 
  AND token = 'fAecqmu7z1rkM0WULgzWU25tF461HTWKzem2yBrBX7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}