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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04a9a195e9c7c06d7356c2f079264d229fa5fad0f00204f19faf531f58708c05' 
  AND token = '1UhMiQn8warf8YTEEV/xNN4emKPMIZkSnpz5co9HND8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}