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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f69c483e301310db9943fcd5012e8cf1cc64bd2f0cb65f8e9bbb00877ad29b2' 
  AND token = 'e2VOpUfDKfS2Zsi5YdBbxTLXn3yBivZE45FqBmkmIdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}