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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0f44b568ec987533a3e972cb39a9fd2247dd911a59ef6cd38bbfa1a8632222' 
  AND token = 'qLlyoDtCPF6m7f8KQuA5COngkGmJTRaUCbhCqLFNAFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}