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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6364dabc68e7160a73245b7a2b2c8165bc7bed11413dc570d185120fcb42740d' 
  AND token = 'MUAkSMWhn7mktUNDdEj/YPWeXs+mC/fTVgE/5huPoM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}