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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c5053841544f06fc5941ea622e248ce42acc62da61901169a2f50a1999a1a1' 
  AND token = 'TPbxud1YyI7dXvZRqObHGgGAzU39AqG67vsKgHHg/yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}