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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6712cf53aeb3702fe2dfa0cb9601e62f6957f77c09e19aa50fdc833b499ebb2b' 
  AND token = 'sAcKdpNRlG6zK3V7uoLLBbCr02WH/NNnmeT28+Kw4Vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}