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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55372fd0aa67c1dcb07628ff9891e2df66dafed3616cc038a5ab23ff0748c1b1' 
  AND token = 'm9pSNTSVDQdKYKmjMXcsEfC2HbL7u2dUPy7tOSxemLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}