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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b1b0b01265a91beeac842ac96898b427c0e6f569cc1076d8fcf7d20262535b' 
  AND token = 'PmLx9zKHzkvgYK3vezaw4HUva2cjXnAtTGtiunACtlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}