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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d11bd306da72b585e4a1b6a1698c71b67bf2125007d0b4820a94f6ecd19b95' 
  AND token = 'fLwN5xMbMx1NSAuS7LkATRHLLrXj/Rg3fxLHZCAYtFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}