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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc5f69078ef94cd795f2a5183cf0c89e975b761908e9d1daf5b64541790177d4' 
  AND token = 'GOpbwVWJ6AcOjaqR8A56TJGbp3/mfgEDip5Wqh8sNLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}