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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5d95e2759e824dfa0f15a43d13b6be5f73057de8ecc59e87021c24d03b8ee39' 
  AND token = 'YhQxhqedz7XX40pSIcI/iEgB4IpbKQeHlTy6Wq1yQOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}