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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab37ae6ffd14cfd48ee3612ed12a344d2656cf1cc3738b361641bfacff7c621' 
  AND token = 'hIsDEjQcPpgnbiV37ABBj/bZVuQ7nTCVuTpFRRHCeks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}