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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f57a63c0d8098b98558693de5e1490a17bebd59f30205a9314de132091379612' 
  AND token = '0O0Fmk0VGh5CbLFL8LOGRAuShtsFoXTf3lz1wDt8710=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}