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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3827667004d2c0ddbe6f2500e5cfc9c5ff452d4e8007b4edfc63c9977680c7e' 
  AND token = 'wLo43IGROJ3jhDWIjHy/C7DPLaqUFh9k5fJJszLJcSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}