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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2782cea9d856585ee952c9e790f4e860ac2cef9fb5ef4cd856dfdee28e8746f' 
  AND token = 'u+GAZ4f9ynyoh9KyCRCf/6+pJAdSelg1wdQq42e877w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}