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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe416a922b6588cfceab824a98852f9464a938b500fa29b07833e714b57c7ea' 
  AND token = 'A4iiQNDzGgFIIUcuZSFU7gQELTakH7sVj0SztMND+Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}