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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33213a05bed942ed68a5878287f26e32b2cb5895058b9646054916a2bd5a921' 
  AND token = 'OOpP+RaIfj4QlgAhV7ol5NbAt9GHuGJAna1T0XaZtK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}