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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb533231e2ba78d15537e98c3d9e60bc23d3ffd024ff3756398b8409c296c4f' 
  AND token = 'DfP+Vl1FzWF1t5JtkyIcTjmFnQX9T1YZoc8GmwmCbNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}