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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246fc2185aeb7154ed0559b0422335ad5021618ef07d282adc92023e23adb28f' 
  AND token = 'OumprwoezeIMXBxOYGX2FciIK4huev/Md10tke0L+7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}