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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae65f3eee27b0d415cb0afd0c1f41cb49a34004a273fd6001f02b72d7afc678' 
  AND token = '3+Wzos+P+/e614HJzX8HBJgZmx7axR41Sj0vOAQ0UkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}