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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81deef284b3c74c6355d116f4dfa3c0fb051a55001845d1508c83c55b77a209' 
  AND token = '27takWaG26PI5dVBKJVWlYAov+bXvPHdh3rXnKuxLPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}