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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280149a18ed5929f411594f7d8892d54176201ee720ec3fa7c133e579a899994' 
  AND token = 'mSwLBN/NZbSBkLBE7biBCRBJepahnG+150aPGptycFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}