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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '981ad2d52d63faede1320999a079deed8c3b3a2c63717249c51faac29e049337' 
  AND token = 'MZ1ZNqgOVbBEAt6wBdCt4D4ELySksIaDR8lkBmYbd+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}