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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d5342df58e747ad296e8866c5066fbe2bd128a49d0da6da26dc6c2d51ad6595' 
  AND token = 'P2NcXh5GwiA+cfEY/SCSjzg7X/X6jblvXWQYMmevq4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}