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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14a5f061d8bacf86cd9d1080bd89072f2fa5f6d9167a66bd22bbad17f9a4d6cb' 
  AND token = 'uoXBNVfehEyLmn7hMN64v6TJBQzKwN2RF5OzqV1tpKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}