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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c33152f9c5a2686079e026d65201c1dcae13746be13585a572fae3b15d47a74' 
  AND token = 'hqAZKcH+KASpeW++lNYssgEb3Xg/j41WullMLiaMt70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}