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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6780b8d50ff82bcd164e9963532b552faf82c65f33d80b1f3a63acb539e976ca' 
  AND token = '+MEnbKbzWZmdx2aY7XAoRnf9sw1Es1Pgc75kVE0d72g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}