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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a080a000ed5275f87177fd7dbf73cb111bf6e7d1a75ee28c20adc241ef52477' 
  AND token = 'xfEpDn8LUJx/ttzdMiVGGERjzwldcBLNrP2nmHmjdu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}