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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c61dbd44fd18a0871a728574572d98311e1e873e6a0c4555d54d862220eb0c' 
  AND token = '78OuE3FlkVFMrTKjfr6wBrXLFXeGllpD8W0+cu/glZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}