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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55f86bdf06b72933b0a3c1f80532ef7372feed2e2a72fcffdee5a291426ff7d7' 
  AND token = 'iU+EKqX7diVhk6ajX8iiOmvbfRB8sINUjnAIFy4V4Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}