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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bfd9a2410c3778dbce10c0de7e61834774c0d25fc0fb08cbe2808ed18cb345c' 
  AND token = 'VEteVTgK4wR5wh1y8Okbvy2bvkUmTVqdtXrFVtwVhQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}