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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '314bf3487e0469cb87625fcd554ea01c8530c3e100fcc2529a1bb93b653f7d0a' 
  AND token = 'HtOZszhMXoF0DRADq7TK3q6vxAjXP19PKq5/4nh/ZU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}