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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b74e78b7ce96061b68d62f17564660a7d350271b8a696db1b645221355bd6b73' 
  AND token = 'q7vTL1Nzf0Xfuahdnxs3XJaIT0lhAgOeqNdefMm0Dz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}