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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd58b73438e38c0b0d086680055b7c1e72d218e3f40f3acf7962c6d871005f5f9' 
  AND token = '8IqxtPLCnex+kaL4t6x4ZWJOw+WhlKxqZg+avOfz6fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}